Welcome to the Harvard Digestive Disease Center
The Harvard Digestive Disease Center (HDDC) creates and supports a community of scientists on the Harvard Longwood Medical School Campus who investigate the molecular, cellular, and developmental biology of the epithelial and other cell types that comprise the mucosal and solid tissues of the alimentary tract – and how these cells function in concert to shape the physiology and pathophysiology of the digestive system. This is the Center’s Theme.
Our Membership includes investigators who explore the physiology and pathophysiology of the epithelial, and enteric endocrine, immune, and nervous systems, as well as the relation of these systems to the gut microbiome and microbial pathogens. We exert influence on Harvard research involving inflammatory, non-inflammatory, and microbially induced diseases of the stomach, intestine, colon, and liver/pancreas, on normal gut-associated tissue and organ development/function, and on the gut microbiome.
The HDDC Research Base includes scientists in 4 major areas of basic and translational research that are fundamental to this effort:
- Cellular, Developmental and Stem Cell Biology
- Innate and Adaptive Mucosal Immunology and Microbial Pathogenesis
- Gut Microbiology and Metabolism
- Clinical and Translational Research on the Alimentary Tract
PI and Director: Wayne Lencer, MD
Co-Director: Richard Blumberg, MD
Please remember to acknowledge the Harvard Digestive Disease Center and NIH grant P30DK034854 in all publications and presentations emerging from HDDC core services, resources, technology, and expertise.