The mission of the Epithelial Cell and Mucosal Immunology Core (Core C) is to provide the infrastructure, biologic resources, expertise, and training for innovative and cross-disciplinary research on the molecular and cell biology of the various cell types forming the mucosal and solid organ tissues of the GI tract.
Core Directors: Wayne Lencer, MD and Jay Thiagarajah, MD, PhD
For access to all services in this Core you must register at our iLab site.
*Procedure to access the equipment in Enders Building: You will need to provide your drivers license to the security guard to access the building.
Analytical Flow Cytometry and Cell Sorting
Analysis of cultured cells, organoid cells, or cells of primary tissues.
Core Scientist: Bin Bao, PhD
Single Cell Transcriptomics and Bioinformatics
Expert consultation, real-time guidance, training, and access to core owned equipment – via collaborations with the Cell Discovery Network and Bioinformatics Core, both at Boston Children’s Hospital.
Core Scientist: José Ordovas-Montanes, PhD
Spatially Resolved Transcriptomics and Bioinformatics
Expert consultation, real-time guidance, training, and access to core owned equipment – with subsidized referrals and collaborations with the Harvard Medical School Single Cell Core.
Core Scientist: José Ordovas-Montanes, PhD
Gastrointestinal Organoid Derivation and Culture
Training and resources for generation and culture of gastrointestinal human and mouse organoids.
Core Scientist: David Breault, MD, PhD
Metabolic and Functional Analysis of Live Cells
Expert consultation, real-time guidance, training, and access to core owned equipment.
Core Scientists: Marco Di Gioia, PhD and Ivan Zanoni, PhD